CBR-470-1

• Background:

  Activator of NRF2 signaling (EC50 ~ 1 µM cellular ARE-LUC assay) .1 It inhibits phosphoglycerate kinase 1 leading to a build-up of methylglyoxal which inactivates KEAP1. It protected SH-SY5Y neuronal cells from MPP+ induced oxidative injury via activation of NRF2 signaling.2

• Conjugation:

  Unconjugated

• Buffer:

  White solid

• Storage Conditions:

  -20°C