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SR9243

CAT: 0498-bs-82932C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82932C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SR9243 is an LXR inverse agonist that significantly inhibits the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression.1 Induces apoptosis in a variety of cancer cell types including SW620 (IC50 = 40 nM), HT-29 (IC50 = 104 nM), DU-145 (IC50 = 15 nM), PC-3 (IC50 = 61 nM), NCI-H23 (IC50 = 72 nM), HOP-62 (IC50 = 26 nM) and MIAPACA-2 (IC50 = 18 nM) . SR9243 is able to promote apoptotic cancer cell death without adversely affecting non-malignant cells.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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