RegisterLogin

Roxadustat

CAT: 0498-bs-82872C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#: bs-82872C-01Size: 5 mg
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Roxadustat (808118-40-3) is a pan-prolyl hydroxylase domain (PHD) inhibitor (IC50 for PHD2 = 591 nM) 1 that stabilizes hypoxia-inducible factor (HIF) leading to erythropoiesis. Currently in clinical trials for treatment of anemia related to chronic kidney disease.2 Roxadustat accelerated cutaneous wound healing and shortened healing time via improvement in epidermal stem cell proliferation and motility3 and increasing angiogenesis4. It displayed radioprotective effects in haematopoietic systems via up-regulation of HIF-1.5 Roxadustat displayed protective effects against atherosclerosis via activation of adipose HIF-2.6
Conjugation
Unconjugated
Buffer
Off-white or white solid
Storage Conditions
-20°C

Related Products

CatalogName

Alternative Products

CatalogName
T2515-01Roxadustat
808118-40-3Roxadustat
7486/50Roxadustat
M16021-01Roxadustat
MBS3606019-01Roxadustat
abx283265-01Roxadustat
RM-R152400-01Roxadustat
317133Roxadustat
HY-13426-01Roxadustat
MBS5812509Roxadustat-d5

Popular Products