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SLF1081851

CAT: 0498-bs-82854C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82854C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SLF1081851 is a sphingosine-1-phosphate transporter (Spns2) inhibitor. It inhibited sphingosine-1-phosphate (S1P) release in HeLa cells: IC50 = 1.93 µM. SLF1081851 is active in vivo and decreased lymphocyte counts and plasma S1P levels in mice and rats. Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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