Products for Research Use Only

GSK2636771

CAT: 0498-bs-82814C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82814C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GSK2636771 is a potent, selective (>1000-fold over α, 10-fold over δ, and >2000-fold over γ), and orally bioavailable inhibitor of PI3Kß (IC50 = 5.2 nM) .1 Active in vitro against multiple types of PTEN-deficient cancer cells. GSK2636771 potently blocked migration and invasion of DU145 prostate cancer cells.2 GSK2636771 has also been identified as a GPR39 agonist.3
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C