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Gilteritinib

CAT: 0498-bs-82813C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82813C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent inhibitor of FLT3 (IC50 = 5 nM, wild-type FLT3) with more potent activity against all FLT3 mutants.1 It also potently inhibits Axl (IC50 = 41 nM) . Clinically useful in the treatment of acute myeloid leukemia. Gilteritinib has also been shown to inhibit glutamine uptake and utilization via downregulation of glutamine transporters.2
Conjugation
Unconjugated
Buffer
Off-white to pale pink solid
Storage Conditions
-20°C

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