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CPI-444

CAT: 0498-bs-82791C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82791C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CPI-444 (1202402-40-1) is a potent (Ki = 3.54 nM) and selective adenosine A2A receptor antagonist. It blocked the induction of cAMP induced by NECA in HEK-293 cells with an IC50 = 17.03 nM. CPI-444 monotherapy or in combination with anti-PD-1, anti-PD-L1, and anti-CTLA-4 induced T-cell-mediated tumor responses, inhibited tumor growth, and enabled antitumor immune memory.1,2 Currently in clinical trials for multiple cancers.3
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
-20°C

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Alternative Products

CatalogName
T7183-01CPI-444
A19242-10CPI-444 10mg
A19242-5CPI-444 5mg
C12087-5mgCiforadenant (CPI-444)
A19242-100CPI-444 100mg
A19242-25CPI-444 25mg
A19242-1CPI-444 1mg
S6646-2mgCiforadenant  (CPI-444)
A19242-50CPI-444 50mg
A19242-10mM-DCPI-444 10mM * 1mL in DMSO

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