Raltitrexed

• Background :

  Raltitrexed is an inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil.1,2 It is also an inhibitor of the methyltransferase G9a (IC50 = 120 nM) and decreased Aß aggregates in C. elegans indicating therapeutic potential for the treatment of Alzheimer’s disease.3

• Conjugation :

  Unconjugated

• Buffer :

  Pale yellow solid

• Storage Conditions :

  -20°C