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CPI203

CAT: 0498-bs-82778C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82778C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CPI203, a JQ1 analog, is a potent and selective inhibitor of the BET bromodomain BRD4 (IC50 = 26 nM) .1 It helps promote the maintenance of hematopoietic stem cells via repression of Myc expression.2 CPI203 reversibly suppressed intestinal stem cell differentiation in a mouse model.3 It enhanced the expansion of human cord blood hematopoietic stem cells without losing cell viability.4 CPI203 displays synergistic antitumor activity with various agents including lenalidomide5, bortezomib6, and PARP inhibitors7.
Conjugation
Unconjugated
Buffer
White to off-white solid
Storage Conditions
-20°C

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