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SGC-iMLLT

CAT: 0498-bs-82776C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82776C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent (IC50 = 260 nM) inhibitor of the YEATS domain of MLLT1/3.1 YEATS domain containing proteins bind acetyl and crotonyl marks on histone tails. Selective against the two other human YEATS domains YEATS2/4 and 48 bromodomains. YEATS containing MLL-ENL leukemic cells display increased sensitivity to SGC-iMLLT versus control AML cells.2
Conjugation
Unconjugated
Buffer
Off-white to beige solid
Storage Conditions
-20°C

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