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SGC-iMLLT

CAT: 0931-T12886Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T12886Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2255338-25-9
Target
Epigenetic Reader Domain, Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.9992
Bioactivity
SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor (IC50 = 0.26 μM), and is a first-in-class chemical probe displaying cellular target engagement of MLLT1 (Kd = 0.129 μM) and MLLT3 (Kd = 0.077 μM) .
Smiles
C[C@H]1CCCN1Cc1nc2cc(NC(=O)c3ccc4n(C)ncc4c3)ccc2[nH]1
Molecular Formula
C22H24N6O
Molecular Weight
388.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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