SGC-iMLLT

• Target:

  Epigenetic Reader Domain|||Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9992

• Bioactivity:

  SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor (IC50 = 0.26 ?M), and is a first-in-class chemical probe displaying cellular target engagement of MLLT1 (Kd = 0.129??M) and MLLT3 (Kd = 0.077??M) .

• Smiles:

  C[C@H]1CCCN1Cc1nc2cc (NC (=O) c3ccc4n (C) ncc4c3) ccc2[nH]1

• Molecular Formula:

  C22H24N6O

• Molecular Weight:

  388.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2255338-25-9