Selinexor

CAT: 0498-bs-82754C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82754C-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Selinexor is a potent inhibitor of the nuclear export receptor, chromosome region maintenance 1 (CRM1; Exportin-1 (XPO1) ) . It exhibited potent growth suppression in various T-cell acute lymphoblastic leukemia (T-ALL) cells (IC50’s = 34-203 nM) 1 and pancreatic cancer cells (IC50 ~ 150 nM) 2. Selinexor is being investigated as a possible chemotherapeutic in treating multiple types of cancer.3-8 Currently in clinical trials.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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