Eltrombopag

• Background:

  A novel, orally active, small molecule human thrombopoietin receptor (TPO-R) agonist, EC50=0.27 M.1,2 Maintains human hematopoietic stem and progenitor cells under inflammatory conditions.3 Promotes DNA repair in human hematopoietic stem and progenitor cells.4 Acts as a powerful chelator of cellular and extracellular iron (III) .5 Stimulates hematopoietic stem cells via a TPO-R-independent mechanism involving iron chelation.6

• Conjugation:

  Unconjugated

• Buffer:

  Orange solid

• Storage Conditions:

  -20°C