R-59022

• Background :

  R-59022 is a diacylglycerol kinase (DAGK) inhibitor, nonselective for DAGK isotypes (IC50=2.8 µM in intact platelets) .1 Induces autophagy and apoptosis in NG108-15 neuronal cells via an mTOR-independent mechanism.2 Prevents conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes.3 Blocks filovirus internalization in host cells.4

• Conjugation :

  Unconjugated

• Buffer :

  White solid

• Storage Conditions :

  -20°C