Products for Research Use Only

TPPU

CAT: 0498-bs-82680C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82680C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer’s disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C