TPPU (Standard)

CAT: 0804-HY-101294RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-101294RSize:1 Each
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
TPPU (Standard) is the analytical standard of TPPU (HY-101294) . This product is intended for research and analytical applications. TPPU is a soluble epoxide hydrolase (sEH) inhibitor with IC50 values of 37 and 3.7 nM for monkey and human sEH, respectively.
CAS Number
[1222780-33-7]
Target
Epoxide Hydrolase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(NC1=CC=C(OC(F)(F)F)C=C1)NC2CCN(C(CC)=O)CC2
Molecular Formula
C16H20F3N3O3
Molecular Weight
359.34
References & Citations
[1]Ulu A, et al. Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys. Br J Pharmacol. 2012 Mar;165 (5) :1401-12.|[2]Ostermann AI, et al. Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1- (1-propanoylpiperidin-4-yl) -3-[4- (trifluoromethoxy) phenyl]urea (TPPU) : Resulting drug levels and modulation of oxylipin pattern. Prostaglandins Other Lipid Mediat. 2015 Sep;121 (Pt A) :131-7.|[3]Ren Q, et al. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proceedings of the National Academy of Sciences of the United States of America (2016), 113 (13), E1944-E1952.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Popular Products