Erastin

• Background :

  Ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response.2 Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis.3 Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3) .4

• Conjugation :

  Unconjugated

• Buffer :

  White solid

• Storage Conditions :

  -20°C