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Erastin

CAT: 0026-2231-1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0026-2231-1Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Erastin is a selective antitumor agent that displays greater lethality in human tumour cells harbouring mutations in the oncogenes HRAS, KRAS or BRAF. It binds to mitochondrial volatage-dependent anion channels (VDAC) proteins, more specifically on VDAC2 and alters its gating. Erastin rapidly induces an oxidative, non-apoptotic cell death in several human tumors harboring activating mutations in the RAS-RAF-MEK signaling.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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