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AC1903

CAT: 0498-bs-82669C-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82669C-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
-20°C

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