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Torin 1

CAT: 0498-bs-82630C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82630C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent and selective ATP-competitive mTOR inhibitor, IC50=2 and 10 nM for mTORC1 and mTORC2 respectively.1,2 Active in vivo at inhibition of mTOR-mediated effects in mice (20 mg/kg) .2 Induces autophagy.3 Torin 1-mediated enhancement of TFEB-mediated autophagy alleviates neuronal death in oxidative stress-induced disease models.4 Downregulates NGF expression in RSC96 cells.5
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C

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