1,4-DPCA

• Background:

  Potent inhibitor of prolyl 4-hydroxylase (IC50=2-4 μM) 1. Inhibits collagen deposition via inhibition of collagen proline hydroxylation2,3. Subcutaneous injection of a 1,4-DPCA containing hydrogel into Swiss Webster mice that do not show a regenerative phenotype increased expression of HIF1α over 5 days. Multiple injections led to regenerative wound healing after ear hole punch injury4.

• Conjugation:

  Unconjugated

• Buffer:

  Off-white solid

• Storage Conditions:

  RT