Domoic acid

• Background:

  Kainic acid-type neurotoxin produced by certain species of the marine pennate diatom Pseudo-nitzschia, is responsible for amnesic shellfish poisoning.1 Suspension feeders such as bivalve mollusks can accumulate and retain high amounts of DA in their tissues, threatening human health.2,3 DA is a potent agonist at kainate and AMPA receptors4 and induces convulsive behavior and seizures in rodents5. It induces structural and molecular changes in the developing zebra fish nervous system.6

• Conjugation:

  Unconjugated

• Buffer:

  Solution in water with 5% acetonitrile at 50 µg/0.5 mL

• Storage Conditions:

  -20°C