Sinefungin

• Background:

  Nucleoside S-adenosyl-1-methionine analog. Potent, competitive methyltransferase (protein, DNA, and RNA methyltransferases) inhibitor1,2. IC50 < 1.0 and 2.5 μM for PRMT1 and SET7/9, respectively3. Binds with greater affinity to the adenine-specific DNA methyltransferase M.TaqI than S-adenosyl-L-homocysteine4. Inhibits biofilm formation by Streptococcus pneumoniae5.

• Conjugation:

  Unconjugated

• Buffer:

  Tan solid

• Storage Conditions:

  -20°C