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Myriocin (ISP-1)

CAT: 0498-bs-82385C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82385C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Myriocin is a fungal metabolite with potent immunosuppressant activity.1 It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide.2 It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression.3
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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2567-5Myriocin (ISP-1)
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