Leptomycin B

• Background:

  Inhibitor of nuclear export of proteins. Acts via covalent binding to and inhibiting CRM1/exportin-11. Inhibits the nuclear export of the HIV regulatory protein Rev2. Stabilizes p53 by blocking its nuclear export3.

• Conjugation:

  Unconjugated

• Buffer:

  Solution in ethanol (1mg/ml)

• Storage Conditions:

  -20°C