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Herboxidiene

CAT: 0498-bs-82346C-01Size: 200 µgDry Ice: NoHazardous: No
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CAT#:0498-bs-82346C-01Size:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel polyketide fermentation product produced by Streptomyces chromofuscus, originally discovered by screening for herbicidal activity. Potent and selective inhibitor of spliceosome subunit SF3b.2 Specifically targets SAP155, a subunit of SF3b responsible for pre-mRNA splicing.3 Displays anti-angiogenic activity via down-regulation of VEGFR-2 and HIF-1α.4 Spliceosome inhibitors have attracted enormous attention due to their potential use in cancer treatment.5
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

Alternative Products

CatalogName
112102Herboxidiene

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