TGN-020

• Background:

  Aquaporin 4 channel blocker, IC50 = 3.1 μM.1 Reduces ischemic cerebral edema in a mouse model of focal cerebral ischemia using MRI.2 Increases regional cerebral blood flow as determined in wild-type and AQP-4 knockout mice.3 Reduces brain edema when administered after onset of ischemia in rat models.4

• Conjugation:

  Unconjugated

• Buffer:

  Off-white solid

• Storage Conditions:

  RT