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STF-083010

CAT: 0498-bs-82292C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82292C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo.
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
RT

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