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YM-155

CAT: 0498-bs-82268C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82268C-01Size:5 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4
Conjugation
Unconjugated
Buffer
Tan to yellow solid
Storage Conditions
-20°C

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