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BMS-303141

CAT: 0498-bs-82230C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82230C-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 M. Inhibits lipid biosynthesis, IC50=8 M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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T2337-01BMS-303141
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