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Importazole

CAT: 0498-bs-82229C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82229C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Specifically inhibits importin-β-mediated nuclear import without disrupting transportin-mediated nuclear import or CRM1-mediated nuclear export1. When added to cells during mitosis it impairs the release of an importin- cargo probe and causes defects in spindle assembly. Inhibition of importin-β function is most likely mediated by blocking its interaction with RanGTP. It is an important new tool to probe the function of the importin-/RanGTP pathway2-4. Cell permeable
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
RT

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CatalogName
A4643-50Importazole

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