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Dorsomorphin

CAT: 498-bs-82016C-01Size: 5 mgDry Ice: NoHazardous: No
5 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent, selective and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM) .1 It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. It inhibits bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6) .2 Dorsomorphin has been shown to promote cardiomyogenesis in mouse embryonic stem cells (ESCs) in vitro.3 Induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.4
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C

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