Dorsomorphin

• CAS Number :

  866405-64-3

• Target :

  TGF-beta/Smad|||AMPK|||Autophagy

• Related Pathways :

  Chromatin/Epigenetic|||Stem Cells|||Autophagy|||PI3K/Akt/mTOR signaling

• Purity :

  0.9948

• Bioactivity :

  Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity.

• Smiles :

  C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1

• Molecular Formula :

  C24H25N5O

• Molecular Weight :

  399.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C