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CD271 Antibody

CAT: 0013-GTR17857328Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR17857328Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal antibody to CD271 which is low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. It can mediate cell survival as well as cell death of neural cells. CD271 is useful for the detection of all cells expressing p75NTR on their surface, such as motor neurons cholinergic basal forebrain neurons, activated Schwann cells, olfactory ensheathing glial cells.
Product Name Alternative
TNFRSF16, NGFR, p75NTR, p75NGFR
UniProt
P08138
Reactivity
Feline, Ferret, Human, Primate, Rabbit
Immunogen
Purified CD271 protein isolated from human melanoma cell line A875
Target
CD271
Clonality
Monoclonal
Clone
NGFR5
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation; Cell Biology
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Immunohistochemistry (paraffin sections) : Recommended dilution: 1-2 μg/ml; Positive tissue: melanoma, heat-mediated antigen retrieval. Flow cytometry: Extracellular and intracellular staining; recommended dilution: 1-4 μg/ml.
Tested Applications
FC, ICC, IHC-P, IP, WB
Preservative
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Isotype
Mouse IgG1
Entrez
4804

UniProtKB · P08138

Tumor necrosis factor receptor superfamily member 16

TNR16_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P08138
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NGFR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R961, B4E096
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisBiological rhythmsDifferentiationNeurogenesis

Cellular component

Cell membraneCell projectionCytoplasmMembraneSynapse

Molecular function

Developmental proteinReceptor

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

RepeatSignalTransmembraneTransmembrane helix

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