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LRIT3 Antibody

CAT: 0800-RQ8551Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RQ8551Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 is a protein that in humans is encoded by the LRIT3 gene. This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F.
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, ELISA: 0.1-0.5 µg/mL
UniProt
Q3SXY7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An E.coli-derived human recombinant protein (amino acids E50-R573) was used as the immunogen for the LRIT3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This LRIT3 antibody is available for research use only.
Storage Conditions
After reconstitution, the LRIT3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the LRIT3 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Immunofluorescent staining of FFPE human U-2 OS cells with LRIT3 antibody (red) and Beta Tubulin mAb (green) . HIER: steam section in pH6 citrate buffer for 20 min.

UniProtKB · Q3SXY7

Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3

LRIT3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q3SXY7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LRIT3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
C9J1C2, Q6ZTG1
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell projectionEndoplasmic reticulumMembrane

Disease

Congenital stationary night blindnessDisease variant

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainLeucine-rich repeatRepeatSignalTransmembraneTransmembrane helix

Technical term

Proteomics identificationReference proteome

Biological process

Sensory transductionVision

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