Products for Research Use Only

Alpha-Synuclein Antibody / SNCA

CAT: 0800-RQ8886Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0800-RQ8886Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mutations or abnormal accumulation of Alpha-Synuclein are strongly linked to synucleinopathies, including Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Its aggregation into insoluble fibrils is a key pathological hallmark of these conditions. Studying Alpha-Synuclein expression and distribution provides valuable insights into neuronal function, protein misfolding, and neurodegenerative disease mechanisms. Using a high-quality Alpha-Synuclein antibody enables sensitive detection in assays such as western blot, immunohistochemistry, and ELISA. An Alpha-Synuclein antibody from NSJ Bioreagents offers reliable performance for researchers investigating protein aggregation, neurodegenerative disease progression, and potential therapeutic interventions. Selecting the appropriate Alpha-Synuclein antibody is essential for generating reproducible and accurate results in both basic and applied neuroscience research.
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence: 1:50-1:200
UniProt
P37840
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A peptide sequence specific to Alpha-Synuclein was used as the immunogen for the Alpha-Synuclein antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
AGA-19
Applications
WB, IF, IHC-P
Purity
Affinity chromatography
Format
Purified
Limitations
This Alpha-Synuclein antibody is available for research use only.
Storage Conditions
After reconstitution, the Alpha-Synuclein antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the Alpha-Synuclein antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic, cell membrane
Image Legend
IHC staining of FFPE human colon cancer tissue with Alpha-Synuclein antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.