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Zebrafish Rab3Gap1 Antibody

CAT: 0800-RZ1056Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-RZ1056Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rab3 GTPase-activating protein catalytic subunit is an enzyme that in humans is encoded by the RAB3GAP1 gene. This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL
UniProt
Q6NUV0
Host
Rabbit
Reactivity
Zebrafish
Immunogen
An E.coli-derived zebrafish Rab3Gap1 recombinant protein (amino acids N109-Q798) was used as the immunogen for the Zebrafish Rab3Gap1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This Zebrafish Rab3Gap1 antibody is available for research use only.
Storage Conditions
After reconstitution, the Zebrafish Rab3Gap1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Zebrafish Rab3Gap1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
IHC staining of FFPE zebrafish kidney tissue with Zebrafish Rab3Gap1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · Q6NUV0

Rab3 GTPase-activating protein catalytic subunit

RB3GP_DANRE · Danio rerio

View on UniProt ↗
Primary accession
Q6NUV0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
rab3gap1
Protein existence
2: Evidence at transcript level
Organism
Danio rerio (Zebrafish)
Taxonomy ID
7955
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Cellular component

CytoplasmEndoplasmic reticulumGolgi apparatus

Molecular function

GTPase activation

Technical term

Reference proteome

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