Endothall (Standard)

CAT: 0804-HY-113976ARSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-113976ARSize:1 Each
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Description
Endothall (Standard) is the analytical standard of Endothall. This product is intended for research and analytical applications. Endothall (Endothal) is a protein phosphatase 2A (PP2A) inhibitor with IC50s of 90 nM and 5 µM for PP2A and PP1, respectively. Endothall can be used as an herbicide. Endothall also is useful in cancer chemotherapy[1].
CAS Number
[145-73-3]
Product Name Alternative
Endothal (Standard)
UNSPSC
12352005
Target
Phosphatase; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/endothall-standard.html
Smiles
OC(C1C(C2CCC1O2)C(O)=O)=O
Molecular Formula
C8H10O5
Molecular Weight
186.16
References & Citations
[1]Janetti R Signorelli, et al. Protein phosphatases decrease their activity during capacitation: a new requirement for this event. PLoS One. 2013 Dec 2;8 (12) :e81286.|[2]J P Thièry, et al. Hepatocellular carcinoma cell lines from diethylnitrosamine phenobarbital-treated rats. Characterization and sensitivity to endothall, a protein serine/threonine phosphatase-2A inhibitor. Hepatology. 1999 May;29 (5) :1406-17.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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