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IL-3Rβ Rabbit Polyclonal Antibody

CAT: 1444-APRab12557-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:1444-APRab12557-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP) . [provided by RefSeq, Jul 2008], disease:Defects in CSF2RB are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease., domain:The box 1 motif is required for JAK interaction and/or activation., domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding., function:High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor., similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily., similarity:Contains 2 fibronectin type-III domains., subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.
Product Name Alternative
CSF2RB; IL3RB; IL5RB; Cytokine receptor common subunit beta; CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD antigen CD131
Gene Name
CSF2RB
Gene ID
1439
Swiss Prot
P32927
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Cytokine-cytokine receptor interaction; Apoptosis_Inhibition; Apoptosis_Mitochondrial; Apoptosis_Overview; Jak_STAT
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
125kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG

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