PPAR alpha Rabbit Monoclonal Antibody

• Background:

  Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]

• Product Name Alternative:

  PPAR; NR1C1; hPPAR; PPARalpha; PPAR-alpha

• Gene Name:

  PPAR alpha

• Gene ID:

  5465

• Swiss Prot:

  Q07869

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:2000

• Form:

  Liquid

• Buffer:

  Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW:52 kDa; Observed MW:52 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  IgG