BTF3 Rabbit Monoclonal Antibody

• Background:

  When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER) . Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.

• Product Name Alternative:

  NACB; BTF3a; BTF3b; BETA-NAC

• Gene Name:

  BTF3

• Gene ID:

  689

• Swiss Prot:

  P20290

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IP

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100, IP 1:10-1:20

• Form:

  Liquid

• Buffer:

  Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 22 kDa; Observed MW: 22 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Isotype:

  IgG