BTF3 Rabbit Monoclonal Antibody

• Background:

  When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER) . Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.

• Product Name Alternative:

  NACB; BTF3a; BTF3b; BETA-NAC

• Gene Name:

  BTF3

• Gene ID:

  689

• Swiss Prot:

  P20290

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Applications:

  WB, IHC, IP

• Field of Research:

  Immunology

• Purification:

  Affinity Purification

• Dilution:

  WB 1:500-1:1000, IHC 1:50-1:100, IP 1:20-1:50

• Form:

  Liquid

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

• Modification:

  Unmodified

• Molecular Weight:

  Calculated MW: 22 kDa; Observed MW: 22 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

• Isotype:

  IgG