Recombinant Human Insulin

• Background:

  Insulin is a peptide hormone with 51 amino acids that plays a crucial role in regulating glucose homeostasis, cell growth, and metabolism . It is produced by the beta cells of the islets of Langerhans in the pancreas and is secreted in response to elevated blood glucose levels, such as after a meal . Insulin is synthesized as a prohormone called preproinsulin, which consists of 110 amino acids. This is processed to proinsulin, which includes the A-chain, B-chain, and C-peptide, and is then further processed to the active form of insulin with the removal of the C-peptide.

• Product Name Alternative:

  Insulin; INS; IDDM; ILPR; IRDN; MODY10

• Accession Number:

  P01308

• Host:

  Yeast

• Endotoxin:

  ≤10 EU/mg

• Purity:

  Greater than 95% as determined by reducing SDS-PAGE

• Form:

  Lyophilized

• Reconstitution:

  Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

• Molecular Weight:

  6 kDa

• Shipping Conditions:

  The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

• Storage Conditions:

  Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

• Formulation:

  Lyophilized From Acetic acid

• Construct:

  Recombinant Human Insulin is produced by our Yeast expression system and the target gene encoding αlpha chain: G-I-V-E-Q-C-C-T-S-I-C-S-L-Y-Q-L-E-N-Y-C-N & beta chain: F-V-N-Q-H-L-C-G-S-H-L-V-E-A-L-Y-L-V-C-G-E-R-G-F-F-Y-T-P-K-T is expressed.

• Species:

  Human