Products for Research Use Only
RegisterLogin

Recombinant Human PEA15

CAT: 1444-PEH1298-01Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1444-PEH1298-01Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED) -containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis and cancer progression. PEA15 is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. PEA15 blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. PEA15 also inhibits RPS6KA3 activities by holding it in the cytoplasm. In addition, PEA15 inhibits both TNFRSF6 and TNFRSF1A mediated CASP8 activity and apoptosis. At present, PEA15 expression is also a significant prognostic marker in ovarian cancer.
Product Name Alternative
Astrocytic Phosphoprotein PEA-15; 15 kDa Phosphoprotein Enriched in Astrocytes; Phosphoprotein Enriched in Diabetes; PED; PEA15
Accession Number
Q15121
Host
E.coli
Endotoxin
<1 EU/µg as determined by LAL test.
Purity
Greater than 95% as determined by reducing SDS-PAGE
Form
Lyophilized
Reconstitution
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molecular Weight
15.3 KDa
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Conditions
Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Construct
Recombinant Human Phosphoprotein Enriched in Astrocytes of 15 kDa is produced by our E.coli expression system and the target gene encoding Met1-Ala130 is expressed.
Species
Human

Related Products

CatalogName
PCH2530-01Recombinant Human LIF
PCH2504-01Recombinant Human EPO
PCH2503-01Recombinant Human EGF
PCH2500-01Recombinant Human Activin A
PEH1312-01Recombinant Human Persephin
PEH0273-01Recombinant Human CCL8
PEH0270-01Recombinant Human CCL3
PEH0268-01Recombinant Human CCL27
PEH0259-01Recombinant Human CCL11
PEH0253-01Recombinant Human CCL2

Alternative Products

CatalogName
MBS7610507-01Recombinant Human PEA15
OPCA04983-20UGPEA15 Recombinant Protein (Human)
TP726394PEA15 Human Recombinant Protein
E30P10596Recombinant Human PEA15 Protein
TMPJ-01125-01PEA15 Protein, Human, Recombinant
TP720922MPEA15 (NM_003768) Human Recombinant Protein
KMH1536-01Recombinant Human PEA15 Protein, No Tag
HB429012-01Recombinant Human PEA15 Protein, N-His
HY-P71195PEA15, Human
OM302448-01PEA15 Human

Popular Products