Products for Research Use Only

CD195 Antibody (PE)

CAT: 0013-GTR17857484Size: 100 TestsDry Ice: NoHazardous: No
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CAT#:0013-GTR17857484Size:100 Tests
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Description
Mouse monoclonal antibody conjugated to PE which recognizes CD195 that belongs to the G-protein coupled receptor 1 family. It also known as CCR5. It highly expressed in spleen, thymus. CD195 play a role in the control of granulocytic lineage proliferation or differentiation. It acts as a coreceptor for HIV-1 R5 isolates.
Product Name Alternative
CKR5, CCR5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5
UniProt
P51681
Reactivity
Human
Immunogen
CCR5 peptide (Met1-Lys22) KLH conjugate
Target
CD195
Clonality
Monoclonal
Clone
T21/8
Conjugation
PE
Field of Research
Immunology & Inflammation
Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Notes
For research use only.
Applications Notes
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Tested Applications
FC
Preservative
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Isotype
Mouse IgG1 kappa
Entrez
1234

UniProtKB · P51681

C-C chemokine receptor type 5

CCR5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51681
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCR5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
C-C CKR-5, CC-CKR-5, CCR-5, CCR5
EC number
—
Processing
—
Secondary accessions
O14692, O14693, O14695, O14696, O14697, O14698, O14699, O14700, O14701, O14702, O14703, O14704, O14705, O14706, O14707, O14708, O15538, Q9UPA4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

Disease

Diabetes mellitus

PTM

Disulfide bondGlycoproteinLipoproteinPalmitatePhosphoproteinSulfation

Molecular function

G protein-coupled receptorHost cell receptor for virus entryReceptorTransducer

Biological process

Host-virus interaction

Domain

TransmembraneTransmembrane helix