Caffeic acid

• Description :

  Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO) .

• UNSPSC :

  12352005

• Hazard Statement :

  H351

• Target :

  Endogenous Metabolite; Lipoxygenase; TRP Channel

• Type :

  Natural Products

• Related Pathways :

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Caffeic_acid.html

• Purity :

  99.92

• Solubility :

  DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

• Smiles :

  O=C(O)/C=C/C1=CC=C(O)C(O)=C1

• Molecular Formula :

  C9H8O4

• Molecular Weight :

  180.16

• Precautions :

  H351

• References & Citations :

  [1]Pradhananga S, et al. Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice. Eur J Pharmacol. 2015 Sep 5;762:313-21.|[2]Liang G, et al. The protective effect of caffeic acid on global cerebral ischemia-reperfusion injury in rats. Behav Brain Funct. 2015 Apr 18;11:18.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  5-LOX

• CAS Number :

  [331-39-5]