Caffeic acid

• Description:

  Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO) .

• UNSPSC:

  12352005

• Hazard Statement:

  H351

• Target:

  Endogenous Metabolite; Lipoxygenase; TRP Channel

• Type:

  Natural Products

• Related Pathways:

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Caffeic_acid.html

• Purity:

  99.92

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

• Smiles:

  O=C(O)/C=C/C1=CC=C(O)C(O)=C1

• Molecular Formula:

  C9H8O4

• Molecular Weight:

  180.16

• Precautions:

  H351

• References & Citations:

  [1]Pradhananga S, et al. Caffeic acid exhibits anti-pruritic effects by inhibition of multiple itch transmission pathways in mice. Eur J Pharmacol. 2015 Sep 5;762:313-21.|[2]Liang G, et al. The protective effect of caffeic acid on global cerebral ischemia-reperfusion injury in rats. Behav Brain Funct. 2015 Apr 18;11:18.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• Isoform:

  5-LOX

• CAS Number:

  331-39-5