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8-OHDG antibody

CAT: 0710-FNab11005Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab11005Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.
Synonyms
8-hydroxy-2'-deoxyguanosine|2'-Deoxy-8-oxoguanosine|7,8-Dihydro-8-oxo-2'-deoxyguanosine|8-Oxo-7,8-dihydro-2'-deoxyguanosine|8-Oxo-7,8-dihydrodeoxyguanosine|2'-Deoxy-8-oxo-D-guanosine|8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-dG|2'-Deoxy-8-hydroxyguanosine
Host
Rabbit
Reactivity
Species independent
Immunogen
KLH conjugated 8-OHdG
Target
8-OHDG
Clonality
Polyclonal
Isotype
IgG
Purification
Immunogen affinity purified
Dilution
IHC: 1:50 - 1:500; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.06% PC300 and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
IHC, IF

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