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Recombinant Notch1 Antibody

CAT: 0667-RC-16756-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-RC-16756-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Neurogenic locus notch homolog protein 1, Notch 1, hN1, Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation, NEXT, Notch 1 intracellular domain, NICD]
Gene Name
NOTCH1
Gene ID
4851
UniProt
P46531
Antigen Species
Human
Reactivity
Human, Mouse, Rat
Cross Reactivity
Not tested
Immunogen
A synthesized peptide derived from human Notch1
Partner Proteins
Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation; NEXT; Notch 1 intracellular domain; NICD]
Clone
K01_4R82
Conjugation
Unconjugated
Applications
IHC&WB&ICC/IF
Validation
IHC&WB&ICC/IF
Purity
≥85%
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Recombinant Antibody
Yes
IHC Dilution
1:50~1:100
WB Dilution
1:500~1:1000
IF Dilution
1:50~1:200
Formulation
10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Antibody Type
Monoclonal
Gene Name Synonym
TAN1
Target Alternative Name
Notch1
Panel Description
Neuroscience Biomarkers
Host or Source
Rabbit
Protein Name
Notch receptor 1
WB Description
Succeed
IHC description
Succeed
IF/ICC description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG

UniProtKB · P46531

Neurogenic locus notch homolog protein 1

NOTC1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P46531
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOTCH1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Notch 1, hN1
EC number
—
Processing
Precursor
Secondary accessions
Q59ED8, Q5SXM3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDevelopmental proteinReceptor

Biological process

AngiogenesisDifferentiationNotch signaling pathwayTranscriptionTranscription regulation

Domain

ANK repeatEGF-like domainRepeatSignalTransmembraneTransmembrane helix

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondPhosphoproteinUbl conjugation

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