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MYLK Antibody

CAT: 0667-KC-1191-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-1191-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Myosin light chain kinase, smooth muscle, MLCK, smMLCK, Kinase-related protein, KRP, Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]
Gene Name
MYLK
Gene ID
4638
UniProt
Q15746
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human MYLK
Target
PP-5084
Partner Proteins
Myosin light chain kinase; smooth muscle; MLCK; smMLCK; Kinase-related protein; KRP; Telokin) [Cleaved into: Myosin light chain kinase; smooth muscle; deglutamylated form]
Clone
K06279_1H8
Conjugation
Unconjugated
Applications
Top_IHC
Validation
Top_IHC
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 31%, Pig - 95%, Cynomolgus monkey - 100%
Purity
≥85%
Cores
IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
92%
Recombinant Antibody
Not recombinant
IHC Dilution
1:200
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
MLCK; MLCK1; MYLK1
Target Alternative Name
MYLK
Host or Source
Mouse
Protein Name
Myosin light chain kinase
WB Description
Fail (A549)
IHC description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG2b

UniProtKB · Q15746

Myosin light chain kinase, smooth muscle

MYLK_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15746
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYLK
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MLCK, smMLCK
EC number
2.7.11.18
Processing
—
Secondary accessions
B4DUE3, D3DN97, O95796, O95797, O95798, O95799, Q14844, Q16794, Q17S15, Q3ZCP9, Q5MY99, Q5MYA0, Q6P2N0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UBY6, Q9UIT9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondPhosphoprotein

Molecular function

Actin-bindingCalmodulin-bindingKinaseSerine/threonine-protein kinaseTransferase

Coding sequence diversity

Alternative promoter usageAlternative splicing

Disease

Aortic aneurysmDisease variant

Ligand

ATP-bindingCalciumMagnesiumMetal-bindingNucleotide-binding

Cellular component

Cell projectionCytoplasmCytoskeleton

Domain

Immunoglobulin domainRepeat

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