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TREM1 Polyclonal Antibody

CAT: 0763-AN007220L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-AN007220L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TREM-1 (Triggering Receptor Expressed on Myeloid cells) is a type I transmembrane protein having a single Ig-like domain. It associates with the adapter protein, DAP12, to deliver an activating signal. Several other TREM family members have been reported that are structurally similar but share less than 30% amino acid identity. TREM-1 is expressed on blood neutrophils and a subset of monocytes, and expression is up-regulated by bacterial LPS.
Abbreviation
TREM1
UniProt
Q9NP99
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human TREM1 protein expressed by Mammalian
Target
TREM-1 (Triggering Receptor Expressed on Myeloid cells) is a type I transmembrane protein having a single Ig-like domain. It associates with the adapter protein; DAP12; to deliver an activating signal. Several other TREM family members have been reported that are structurally similar but share less than 30% amino acid identity. TREM-1 is expressed on blood neutrophils and a subset of monocytes; and expression is up-regulated by bacterial LPS.
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Immunology
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26 kDa
Observed Molecular Weight
25 kDa
Isotype
IgG

UniProtKB · Q9NP99

Triggering receptor expressed on myeloid cells 1

TREM1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NP99
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TREM1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TREM-1
EC number
—
Processing
Precursor
Secondary accessions
B4DWG2, K7EJW1, Q53FL8, Q5T2C9, Q86YU1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityImmunityInnate immunity

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

Molecular function

Receptor
Product Datasheet
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